


glp 1 agonist small molecule Binding sites and design strategies for small molecule GLP-1R agonists
Marsoni
M251S
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Friday, May 29
Orforglipron: The First Approved Oral Non Peptide GLP 1R Agonist for Obesity https: t.co tBVwBAYAz8 Orforglipron is now FDA approved for obesity, marking a major milestone for orally available small molecule GLP 1 therapies. Originally discovered State tying weight loss drug use to new program State Affairs Pro Semaglutide acetate CAS 910463 68 2 Adipogen Life Sciences GLP 1 Agonist Employers Weighing the Obesity Drug Question MedBen Rx
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Great for my hot rod!
Size: 5 Quart, Style: Full Synthetic, Configuration: 0W-40
Perfect oil for my hot rod! Add a bottle of zinc and you get great low temp flow as well as good heat protection. As a 0W it flows quickly for good start up protection and the 40W means I get good protection as temps rise. My car has a flat tappet hydraulic cam so I add a bottle of zinc. Has worked great!
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Reviewed in the United States on March 19, 2026
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European oil… Japanese engine… zero regrets 🇪🇺➡️🇯🇵
Size: 5 Quart, Style: Full Synthetic, Configuration: 0W-40, Size: 5 Quart, Style: Full Synthetic, Configuration: 0W-40
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This engine is not stock, not delicate, and definitely not living an easy life. It sees spirited driving, boost, and the occasional questionable decision. After switching to Mobil 1 0W-40, cold starts are smoother, oil pressure is rock solid, and the motor just feels happier. No weird noises, no drama, no oil consumption surprises.
The viscosity is perfect for a performance Subaru build, especially if you’re running tighter tolerances or want strong protection under heat and load. It’s thick enough when hot, flows great when cold, and inspires confidence every time I turn the key.
Is it technically “European”? Sure.
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Would absolutely buy again—passport not required.
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